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Acknowledgments The neurovascular unit concept was developed by the entire research community, not just any one single scientist. The author apologizes to many colleagues who could not be included as coauthors and whose work could not be cited, due to…
Introduction Brain pathophysiology is influenced by a dynamic balance between deleterious and beneficial responses to the initial insult . Stroke and brain injury trigger a wide spectrum of neurovascular perturbations, glial activation, and secondary neuroinflammation that may all amplify neuronal…