Introduction Connective tissue tumors presenting primarily in the skin are relatively common. Because the majority of such lesions are benign and clinically nondistinctive they are sometimes neglected by clinicians. However, histologically they constitute a complex group of tumors showing various…
Classification of lymphomas The classification of lymphomas and hematopoietic neoplasms has undergone radical changes in philosophy and diagnostic criteria since the early days of Lukes and Collins, Rappaport, and the subsequent Updated Kiel classification and the Working Formulation. The majority…
Ephelide Clinical features Ephelides (freckles) are extremely common lesions that present as clusters of small (approximately 2.0 mm in diameter), uniformly pigmented macules ( Fig. 25.1 ). They are directly related to exposure to sunlight and are much more conspicuous in…
Introduction A distinctive phenomenon of the human evolutionary process is the loss of a great proportion of the body hair. Vestiges of hair remain in areas such as the scalp, axillae, genital areas, and face. Among the many species of…
Viral Infections Common wart The common wart (verruca vulgaris) is caused by infection with human papillomavirus (HPV) ( Fig. 18.1 ). HPV is a DNA virus of the papovavirus family. The number of known HPV genotypes currently stands at more…
Lupus erythematosus Lupus erythematosus is a complex disorder associated with numerous clinical signs and symptoms and a wide range of laboratory abnormalities. It shows a spectrum of varying prognoses, ranging from a benign, solely cutaneous variant (localized discoid) through to…
Introduction This section concerns itself principally with dermatological disorders specific to the anogenital skin. Many of the dermatological conditions that present in the skin elsewhere sometimes affect the anogenital area although this site may be one of predilection. Clinical and…
Inflammatory diseases of the subcutaneous fat are a source of considerable confusion and often cause diagnostic difficulty to clinicians and pathologists alike. This stems in part from the use of classifications and clinical descriptions based on time-honored but outdated literature.…