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Video 11.1 Thyroid Nodule Fine-Needle Aspiration. Video 11.2 Fine-Needle Aspiration Slide Preparation. Introduction Fine-needle aspiration (FNA) is an essential test in the evaluation of a patient with a thyroid nodule. The result of the FNA determines, in large part, whether…

In the United States, the cytology laboratory is one of the most regulated of all the laboratories involved in clinical testing. To effectively manage and work in a cytology laboratory, personnel must be familiar with the relevant regulatory agencies and…

Fine-needle aspiration (FNA) is a safe, minimally invasive, and relatively inexpensive procedure for the diagnosis of selected ovarian lesions. Indications for fine-needle aspiration of the ovary Confirm the benign nature of an incidental cyst discovered during: An infertility workup Pregnancy…

The Kidney Indications and Sampling Methods Fine-needle aspiration (FNA) of the kidney is a useful technique for the diagnosis of selected renal lesions. FNA, as it turns out, is not necessary for most renal masses. In adults, the great majority…

Discovering a thyroid nodule in a patient raises the specter of malignancy. The usual workup includes an ultrasound examination, followed by fine-needle aspiration (FNA) if the nodule meets biopsy criteria. Thyroid nodules are very common, although the prevalence depends on…

The lumbar puncture (spinal tap) was introduced in 1891, , and in 1904 a French neurologist first described malignant cells in cerebrospinal fluid (CSF). Since then, preparatory methods have been refined and diagnostic features described in a number of monographs…

Peritoneal washing cytology (PWC) was introduced in the 1950s as a way to identify microscopic spread of cancer not visible by gross inspection of the peritoneal surface. In some cancer patients, positive PWC may be the only evidence of metastatic…

The pleural, pericardial, and peritoneal cavities are lined by a single layer of flat mesothelial cells called the serosa . Normally, these cavities are collapsed and contain only a small amount of fluid (50 mL in each pleural cavity in…

The 20th century witnessed a remarkable decline in the mortality from cervical cancer in developed countries, an achievement attributable to the implementation of the Papanicolaou (Pap) test. In the 1930s, before Pap test screening was introduced, cervical cancer was the…