Hypertension is a key risk factor in the pathophysiology of atherosclerosis and the development of cardiovascular diseases (CVD) including peripheral artery disease (PAD). Available evidence related to PAD and hypertension is largely extrapolated from subgroup analyses of larger trials of…
Intimal hyperplasia represents the healing response to vascular injury as well as the adaptive response to developmental or physiologic events. Injury induces a progressive structural change within the blood vessel lumen that begins with the disruption of endothelial barrier function…
Introduction Thrombolytic agents comprise a diverse group of compounds that indirectly initiate the lysis of a thrombus. After the initiation of the coagulation cascade, fibrinolytic mechanisms are concomitantly activated to prevent unconstrained thrombosis. Fibrinolysis begins with the cleavage of proenzyme…