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Acknowledgments This work was partially supported by grants from the National Institute of Neurological Disorders and Stroke (NINDS) including 5R01 NS083405 and 5R01 NS084857 and 5T32 NS077889 and with funds from the Kentucky Spinal Cord & Head Injury Research Trust.…
Introduction Oxygen-free-radical-induced membrane lipid peroxidation (LP) is a highly validated secondary injury mechanism that occurs in focal and global cerebral ischemia and subarachnoid hemorrhage (SAH). It has been firmly established as a major contributor to multiple aspects of ischemic, postischemic,…