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Summary of Key Points Cancer is characterized by genetic and epigenetic instability leading to both unique and sometimes common mutations and “ectopic” overexpression of genes not normally expressed in the tissue of origin. Cancer-specific proteins arising as a result of…
Therapeutic vaccination for cancer continues to be a major approach to the overall immunotherapy of cancer. Historically, interest in cancer immunology stemmed from the perceived potential activity of the immune system as a weapon against cancer cells. In fact, the…