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Tag Dieter Metze

Disorders of keratinization

Ichthyosis The term ichthyosis (Gr. ichthys , fish) is applied to a number of heterogeneous genetic disorders characterized by permanent and generalized abnormal keratinization. The clinical features range from mild involvement, often passed off as ‘dry skin’ (xerosis), through to…

Palmoplantar Keratodermas

Key features ▪ Palmoplantar keratodermas can be inherited or acquired ▪ The three major patterns of involvement are diffuse, focal, and punctate ▪ The clinical presentation may be different on the hands and feet, e.g. diffuse on the soles and…