3.1 Introduction Barrett’s esophagus (BE) occurs in the setting of chronic gastroesophageal reflux disease (GERD). It is characterized by conversion of the normal esophageal squamous epithelium into metaplastic columnar epithelium . Since its original description by Tileston et al. there…
3.1 Introduction Barrett’s esophagus (BE) occurs in the setting of chronic gastroesophageal reflux disease (GERD). It is characterized by conversion of the normal esophageal squamous epithelium into metaplastic columnar epithelium . Since its original description by Tileston et al. there…
Approach To Evaluating Colitis Pathologists are asked to evaluate colorectal biopsy specimens for a variety of reasons, but often only a pattern of injury can be identified, at best. This evaluation is performed with the hope that a specific diagnosis…
Introduction Inflammatory disorders of the esophagus are extremely common. Among the most common is gastroesophageal reflux disease (GERD), a chronic condition, affecting as many as 40% of people in the Western world. Because of the ease and frequent use of…
Introduction The conventional approach to teaching about inflammatory disorders of the gastrointestinal (GI) tract is to describe the clinical and histological features of individual disease entities. Unfortunately, rendering a specific diagnosis is not always possible when evaluating mucosal biopsies of…