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The biliary tract is lined by simple columnar epithelial cells of foregut origin ( Fig. 47.1 ). The vast majority of biliary neoplasms arise from this cell type and therefore show major similarities to other foregut tumors, particularly those of…

Introduction And Classification Probably the most common problems in the diagnosis of pancreatic neoplasms are the distinction of invasive ductal adenocarcinoma from its mimics and the preoperative evaluation of cystic lesions, which are increasingly recognized. Solid, cellular pancreatic neoplasms present…

Acknowledgment The authors are indebted to Dr. Hulya Sahin Ozkan, Dr. Kerem Ozcan, and Ms. Rhonda Everett for their extensive contributions in the preparation of this chapter. Neuroendocrine Cell System of the Gastrointestinal Tract Neuroendocrine cells in the gastrointestinal (GI)…

Terminology and Classification Tumors of the endocrine pancreas are called pancreatic neuroendocrine neoplasms (PanNENs). PanNEN, like the neuroendocrine neoplasms (NENs) of the gastrointestinal tract, are stratified into two major groups ( Table 20.1 ), the well-differentiated NENs called pancreatic neuroendocrine…

Classification and General Features The classification and nomenclature used in this chapter are based on those proposed by the World Health Organization (WHO) in 2017 and 2019. Its premise is that the cellular phenotype of the tumors of the pancreas…