Introduction The paratesticular region includes the testicular tunics, efferent ductules, epididymis, spermatic cord, and vas deferens. Most studies of paratesticular region pathology include the rete testis despite its intratesticular location. Numerous rare and interesting lesions arise in this region, including…
Introduction The seminal vesicles were described by the Italian anatomist Berengario a Carpi in 1521. These paired androgen-dependent accessory sex glands were first regarded simply as storage sites for semen, but their milky alkaline secretions are now known to constitute…
Benign Epithelial Tumors and Tumor-like Proliferations Prostatic Cysts Giant multilocular prostatic cystadenoma is a large tumor composed of acini and cysts lined by prostatic-type epithelium set in a hypocellular fibrous stroma. This rare tumor arises in men between 28 and…
Embryology and Fetal-Prepubertal History The prostate is derived from the urogenital sinus. During the first 10 weeks of gestation, testosterone from the embryonic testes stimulates ingrowth of epithelial buds into urogenital sinus mesenchyme through a feedback loop. The mesenchyme induces…
Introduction Examination of urine is one of the oldest medical tests, used by Samarians, Babylonians, Egyptians, Indians, and Greeks in their traditional medicine. It was not until after Papanicolaou and Marshall published the first article in 1945 that urine cytology…
Carcinoma of the urinary bladder is the fourth most common malignancy in men, accounting for an estimated 60,490 new cases and 12,240 cancer deaths in the United States in 2018. Significant progress has been made in the diagnosis and treatment…