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This chapter focuses on the pharmacology of the inhaled anesthetics, including their mechanisms of action and clinical effects (pharmacodynamics). Related pharmacokinetic principles of inhaled anesthetics are covered in Chapter 3 . Historical Perspective Discovery of Inhaled Anesthetics The German physician…
Historical Perspective The discovery of drugs with anesthetic properties was a landmark event in the history of pharmacology, medicine, and even civilization, in that it made otherwise painful surgical treatments of disease possible. Without a means of providing anesthesia, it…