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Stratified Adenocarcinoma In Situ


D efinition — A stratified mucin-producing intraepithelial lesion with prominent columnar cell differentiation (also called stratified adenocarcinoma in situ [AIS]).

Clinical Features

Epidemiology

  • Young women, most ranging in age from 20 to 40 years.

  • High-risk human papillomavirus (HPV) associated.

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