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Small Cell Carcinoma of Hypercalcemic Type
D efinition — A malignant rhabdoid tumor associated with hypercalcemia and mutations and inactivation in the SMARCA4 gene.
Clinical Features
Epidemiology
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Presents between childhood and menopause, predominating in the late teens and early twenties.
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Rarely familial, but kindreds with mutations in the SMARCA4 gene have recently been described.
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