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p53-Positive Endometrioid Adenocarcinoma
D efinition — A common conundrum in endometrial cancer classification in which an endometrioid histology coexists with strong p53 staining.
Clinical Features
Epidemiology
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Outcomes for serous carcinoma are distinctly less favorable relative to both low- and high-grade endometrioid carcinomas.
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Some tumors do not readily fall into either category, specifically those with both endometrioid histology and a high level of p53 expression.
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