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Inability to maintain volitional intake (in the setting of a functional gastrointestinal tract) and :
Critical illness expected to require an intensive care unit (ICU) stay of more than 2 days
Poor nutritional status
Weight loss and nutrient depletion
Multiple comorbid conditions
Failure to eat for more than 7 days
Inability to tolerate enteral nutrition:
Mechanical bowel obstruction
Peritonitis
Hemodynamic compromise (e.g., starting or escalating dose of vasopressor[s] in a previously stable patient)
Short gut (relative contraindication)
Severe cranial or facial fracture(s) or deformity
Esophageal obstruction or recent surgery
Esophageal or gastric varices
Coagulopathy (relative contraindication)
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