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A healthy 12-year-old boy presents for reduction of a humerus fracture. Anesthesia is induced with sevoflurane. Fifteen minutes later, there is an abrupt increase in end-tidal carbon dioxide to greater than 70 mm Hg. He becomes tachycardic, with a heart rate of 150 beats per minute, and his temperature increases from 36.7°C to 39.4°C.
The author wishes to thank Dr. Karen M. Van Tassel and Dr. Scott R. Schulman for their contributions to the previous edition of this chapter.
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