Implantation Site Nodule


D efinition A collection of extravillous trophoblasts within hyalinized stroma, indicative of a previous pregnancy.

Clinical Features

Epidemiology

  • Implantation site nodules are common and typically have the same immunophenotype as epithelioid trophoblasts seen in the membranes, maternal surface, and intervillous fibrin.

  • Can be identified in endometrial samples months to years following intrauterine pregnancies.

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