Hyperglycemic Hyperosmolar State


Risk

  • Elderly pts with DM, usually type II

  • Debilitated pts who cannot care for themselves

  • Chronically ill diabetic pts who experience exacerbation of an underlying comorbidity

  • Incidence increased in African Americans, Hispanics, and Native Americans

Perioperative Risks

  • Severe hypovolemia and hemodynamic instability

  • Presence of diffuse organ system damage from poor glycemic control

  • Altered mental status and increased risk of pulmon aspiration

  • Periop stress causing further elevations in serum glucose

Worry About

  • Cause of hyperglycemic hyperosmolar state.

  • Volume status and potential hemodynamic instability.

  • Electrolyte and acid-base abnormalities increase the risk of cardiac arrhythmias.

Overview

  • Serious metabolic condition characterized by hyperglycemia, hyperosmolarity, and dehydration

  • Is one of several potentially fatal states associated with poorly controlled DM

  • Requires aggressive treatment and close electrolyte and hemodynamic monitoring

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