Gastrointestinal Stromal Tumor


D efinition Ovarian involvement is a rare metastatic presentation of this tumor.

Clinical Features

Epidemiology

  • Most common mesenchymal tumor of the gastrointestinal tract.

  • Driven by oncogenic KIT or PDGFRA mutations.

  • Most common is an in-frame mutation of exon 11 in the c-KIT gene.

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