Cancer of the colon and rectum (colorectal cancer [CRC]) is a major cause of cancer-associated morbidity and mortality in North America, Europe, and other regions with similar lifestyles and dietary habits. CRC is the fourth most common newly diagnosed internal…
Colorectal cancer (CRC) is the third most common cancer diagnosed in the USA. In 2020, it is estimated that 147,951 new cases of CRC will be diagnosed, and that approximately 53,200 deaths would result. Adenomatous polyps, including conventional adenomas and…
Small intestinal (SI) tumors (tumors of the duodenum, jejunum, and ileum) are uncommon in comparison with those occurring elsewhere in the GI tract. Whereas the SI is approximately 20 ft long and comprises 75% of the length of the GI…
Ileus and pseudo-obstruction refer to intestinal dysmotility syndromes that have signs, symptoms, and the radiologic appearance of obstruction (i.e., a dilated viscus) in the absence of a mechanical cause. These conditions—which may be acute, chronic, or acute on chronic—affect the…
Severe narrowing or occlusion of the intestinal lumen results in the accumulation of air and fluid in the bowel proximal to the point of obstruction and is associated with a range of clinical signs and symptoms. The location of the…
IBS is an important disease entity because of its high prevalence, substantial morbidity, and enormous costs. In the USA, 7% to 16% of adults report symptoms compatible with IBS, for which up to 50% will consult a GI physician. In…
Acknowledgment The authors would like to acknowledge Drs. Benny Liu, Indhu Subramanian, and Robert Wong for their review and counsel during the development of this chapter. Historically, descriptions and investigations of diverticular disease of the colon are a relatively modern…
Acknowledgment The author would like to acknowledge the significant contributions of Richard H. Turnage, MD, and Kfir Ben-David MD, to prior editions of this chapter. Historical Perspective Leonardo da Vinci was the first to describe the anatomic location of the…
Before the routine use of endoscopic imaging with capsule endoscopy (CE) and deep enteroscopy, discrete ulcers of the small and large intestine were thought to be rare but associated with a broad spectrum of diseases. Similarly, the classic literature on…
Acknowledgment We are indebted to Dr. Scott J. Boley, who worked for decades to lay the groundwork for this chapter and who played a critical role in preparing earlier editions. Intestinal ischemia produces a broad spectrum of disorders depending on…