Uropathology

Squamous cell carcinoma of the penis, usual type

Definition Invasive squamous cell carcinoma (SCC) with a varying degree of keratinization that cannot be classified as other histologic subtypes morphologically; also termed typical, conventional, or SCC, not otherwise specified (NOS) Clinical features You’re Reading a Preview Become a Clinical…

Differentiated penile intraepithelial neoplasia

Definition Non-HPV-related premalignant precursor lesion of the penis characterized by cytologic atypia and abnormal epithelial maturation in the squamous epithelium lining the glans, coronal sulcus, or foreskin, with no extension beyond the basal lamina. Clinical features Epidemiology Similar to invasive…

Penile intraepithelial neoplasia (PeIN)

Definition Precancerous squamous lesion of the penis Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Squamous hyperplasia of the penis

Definition Benign thickening of squamous epithelium without atypia Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Peyronie disease

Definition Localized fibrotic disorder of the penile tunica albuginea Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Pseudoepitheliomatous keratotic micaceous balanitis

Definition A rare form of balanitis characterized by silvery white plaque with micaceous scaling on glans penis Clinical features Epidemiology Close to 25 cases reported Unknown etiology and pathogenesis Usually seen above 50 years of age (mean age at diagnosis,…

Lichen sclerosus et atrophicus (balanitis xerotica obliterans)

Definition Atrophic condition of the epidermis and dermal connective tissue involving the genital and perianal skin of both males and females; involvement of the glans penis and prepuce is termed balanitis xerotica obliterans Clinical features You’re Reading a Preview Become…

Zoon balanitis

Definition Inflammatory condition of the glans penis characterized by a dense plasma cell infiltrate in the upper dermis; also termed plasma cell balanitis Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Clear cell adenocarcinoma of the urethra

Definition A variant of urethral adenocarcinoma morphologically resembling clear cell carcinoma of the female genital tract arising from the urethral mucosa or periurethral glands Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…

Urethral adenocarcinoma

Definition Adenocarcinoma arising from urothelial lining or periurethral accessory glands Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here