Uropathology

Basal cell hyperplasia

Definition Proliferation of basal cells ranging from focal incomplete involvement of the prostatic glands to florid growth completely lacking luminal cells. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…

Hyperplasia of mesonephric remnants

Definition Rare benign lesion characterized by tubular or acinar proliferation of mesonephric remnants Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in…

Clear cell cribriform hyperplasia

Definition A form of benign prostatic hyperplasia characterized by proliferation of benign glands with cribriform architecture, typically in the transition zone of the prostate. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…

Sclerosing adenosis

Definition A benign lesion of the prostate characterized by a biphasic population of small-sized glands and a cellular and/or hyalinized spindled cell stroma, the former of which can show myoepithelial differentiation (i.e., a metaplastic process). Clinical features You’re Reading a…

Adenosis

Definition Adenosis of the prostate is a pseudoneoplastic lesion, usually in the transition zone, that can mimic prostate adenocarcinoma and consists of a proliferation of crowded glands, arranged in a nodule but without significant cytologic atypia. A synonym is atypical…

Partial atrophy

Definition A benign lesion of the prostate composed of pale glands lined by epithelial cells with dense to vesicular crinkled nuclei and a scant amount of pale to clear cytoplasm, with the nuclei often touching the apical cytoplasmic borders. It…

Postatrophy hyperplasia

Definition Morphologically distinct subtype of focal atrophy Also known as post atrophic hyperplasia Clinical features Epidemiology Present in a minority of prostatic needle biopsy and radical prostatectomy specimens Typically occurs in the elderly; uncommon in young men You’re Reading a…

Cystic atrophy

Definition A distinct form of glandular atrophy characterized by cystically dilated glands with sharp luminal borders. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log…

Simple atrophy

Definition Small, benign glands arranged in nests with reduced cytoplasmic volume in luminal epithelial cells. Simple atrophy maintains relatively normal glandular spacing and reduced luminal diameter. Clinical features Epidemiology Typically affects the elderly with the prevalence and extent of gland…

Granulomatous prostatitis of infectious etiology

Definition Granulomatous prostatitis induced by infectious agents. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here