Definition Variant of prostatic adenocarcinoma composed of pseudostratified columnar cells. Clinical features Epidemiology In pure form, ductal adenocarcinoma accounts for less than 1% of all prostatic adenocarcinomas. Associated with acinar adenocarcinoma in approximately 5% of prostate cancers. Occurs in an…
Definition Squamous differentiation in prostate cancer is exceedingly rare and is more often, yet not exclusively, seen in cases of prior hormone or radiation therapy, and is usually associated with a poor prognosis. In general, the adenocarcinoma component is typically…
Definition A rare variant of prostate carcinoma with a prominent lymphoid infiltrate. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Definition A rare and aggressive variant of prostate carcinoma with pleomorphic and anaplastic features with bizarre and pleomorphic giant cells. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership…
Definition Malignant neoplasm of the prostate that demonstrates epithelial and mesenchymal differentiation (formerly called carcinosarcoma ). Clinical features Epidemiology Rare tumor (fewer than 100 cases reported) Average age is 70 years, with a range of 47–91 years Approximately half of…
Definition A variant of invasive prostatic carcinoma that is morphologically characterized by pseudostratified columnar epithelium, typically arranged in dilated glands with flat or tufted epithelium, and morphologic features that resemble high-grade prostatic intraepithelial neoplasia (HGPIN) but lack basal cells. Some…
Definition A deceptively bland variant of invasive Gleason pattern 3 prostatic carcinoma that is morphologically characterized by dilated (i.e., microcystic) acini (up to 10 times the size of a normal Gleason pattern 3 cancer gland) and bland cytology. Could also…
Definition The diagnosis of mucinous adenocarcinoma of the prostate is established only when extracellular mucin is secreted in sufficient quantity to result in pools of mucin (i.e., colloid-like carcinoma) involving more than 25% of the tumor volume on radical prostatectomy.…
Definition A histologic variant of prostatic adenocarcinoma that resembles benign glandular hyperplasia due to their large-caliber glands with papillary infoldings and occasional presence of corpora amylacea, graded as Gleason 3+3, grade group 1. Clinical features Epidemiology Affects adult men of…
Definition A morphologically distinct variant of prostatic adenocarcinoma characterized by abundant foamy cytoplasm. Clinical features Epidemiology Uncommon Mean age, 65 years, similar to usual-type prostatic adenocarcinoma You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…