Uropathology

Atypical glands suspicious for prostatic carcinoma

Definition Small focus of atypical glands suggestive of, but not diagnostic for, low-grade prostatic adenocarcinoma Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

Prostatic stromal sarcoma

Definition Stromal sarcomas are malignant tumors arising from the specialized prostatic stroma, including malignant phyllodes tumor. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Prostatic stromal tumors of uncertain malignant potential

Definition Stromal tumors of uncertain malignant potential (STUMPs) are tumors arising from the specialized prostatic stroma. Prior synonyms include atypical stromal (smooth muscle) hyperplasia, phyllodes type of atypical stromal hyperplasia, phyllodes tumor, and cystic epithelial-stromal tumor . Clinical features You’re…

Urothelial carcinoma

Definition Urothelial carcinoma involves the prostatic tissue, including primary tumor arising from the prostatic urethra and ducts, and secondary involvement by bladder cancer. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Basal cell carcinoma of the prostate

Definition Basaloid carcinoma in the prostate, composed of malignant prostatic basal cells Includes tumors with adenoid cystic-like histological appearances Clinical features Epidemiology Affects adult men in the 6th decade of life You’re Reading a Preview Become a Clinical Tree membership…

Prostatic basal cell adenoma

Definition Uncommon benign lesion of the prostate composed of a nodular proliferation of basaloid nests or benign glands with prominent basal cells that may obscure the glands. Basal cell hyperplasia extensively involving an adenomatous nodule may be interpreted as basal…

Small cell carcinoma, prostate

Definition A rare histologic variant of prostatic carcinoma akin to that diagnosed in the lung. Clinical features Epidemiology Affects adult men of older age; range, 44–92 years (mean, 69 years) You’re Reading a Preview Become a Clinical Tree membership for…

Well-differentiated neuroendocrine tumor

Definition Low-grade epithelial tumor lacking expression of prostatic markers and demonstrating neuroendocrine differentiation. Similar to its counterpart in other locations. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership…

Prostatic adenocarcinoma with neuroendocrine differentiation

Definition Prostatic adenocarcinoma with neuroendocrine (NE) differentiation (either IHC or light microscopy in Paneth cell–like change) excluding prostatic well-differentiated NE tumor, small cell carcinoma, and large cell NE carcinoma. Clinical features You’re Reading a Preview Become a Clinical Tree membership…