Uropathology

Radiation cystitis

Definition Radiation cystitis is characterized by a bladder lesion caused by irradiation of a pelvic organ for urothelial or nonurothelial malignancies. These lesions are dose- and time-dependent, and their spectrum can range from an inflammatory response to complete bladder retraction.…

Granulomatous cystitis after BCG

Definition Granulomatous inflammation following intravesical therapy with bacillus Calmette-Guérin (BCG) for in situ and high-grade urothelial carcinoma Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

Malakoplakia

Definition Relatively uncommon lesion caused by defects in phagocytic or degradative functions of histiocytes in response to bacteria (gram-negative coliforms) Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership…

Infectious cystitis

Definition Infectious disease of urinary bladder caused by microorganisms (bacteria, viruses, fungi, or parasites) Clinical features Epidemiology Bacterial cystitis Most common cause of cystitis Much more common in women due to short urethra, drier periurethral environment and lack of antibacterial…

Eosinophilic cystitis

Definition Inflammatory condition of the bladder that can be idiopathic but is also associated with a variety of systemic triggers, such as food allergens, systemic allergic conditions like asthma or allergic gastroenteritis, topical insults with chemicals, parasites, systemic drugs, local…

Interstitial cystitis/painful bladder syndrome

Definition Clinical pelvic pain syndrome characterized by bladder pain, urinary urgency, or both, glomerulations or Hunner ulcers visualized at cystoscopy with hydrodistention, and absence of other pathologies (diagnosis of exclusion) Clinical features You’re Reading a Preview Become a Clinical Tree…

Giant cell cystitis

Definition The presence of atypical stromal cells in an otherwise unremarkable bladder Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Follicular cystitis

Definition Inflammatory cystitis characterized by the presence of lymphoid follicles with germinal center formation within the lamina propria Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you…

Polypoid and papillary cystitis

Definition An exophytic reactive lesion forming broad-based polypoid or finger-like papillary structures Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Nephrogenic metaplasia/adenoma

Definition Benign proliferation of glandular epithelium in urinary tract mucosa, most frequently found in the urinary bladder, which are thought to derive from metaplasia of the urothelium, implantation of shed renal tubular epithelium, or both Clinical features You’re Reading a…