Uropathology

Germ cell aplasia, sertoli cell-only syndrome

Definition Azoospermia with seminiferous tubules showing complete absence of germ cells and lined by Sertoli cells only Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

Hypospermatogenesis

Definition Reduced production of spermatozoa without a specific point of interruption Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Maturation arrest

Definition Cessation of germ cell development beyond a specific stage in spermatogenesis. The arrest is most frequently observed at primary spermatocyte, rarely spermatogonial, secondary spermatocyte, or spermatid level. Clinical features Epidemiology Can be idiopathic May have genetic etiologies including trisomy…

Male infertility workup

Definition Decreased production or delivery of spermatozoa or production of abnormal spermatozoa Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Vasculitis

Definition Testicular necrotizing vasculitis (inflammatory destruction of vessels with accumulation of fibrinoid material) that can be seen in various systemic disorders or as an isolated form Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access…

Testicular microlithiasis

Definition Presence of more than five foci of calcification per ultrasound field view randomly distributed in the testicular parenchyma May be due to deregulated phagocytic activity of Sertoli cells (undestroyed apoptotic testicular germinal epithelium in the seminiferous tubules, undergoing calcification)…

Spermatic cord torsion and testicular infarction

Definition Torsion is the complete or incomplete twisting of the spermatic cord with or without associated ischemic necrosis of the testis. Torsion may occur within the tunica vaginalis (intravaginal torsion) or outside to it (extravaginal torsion). Clinical features You’re Reading…

Adrenal cortical rests

Definition Adrenal cortical rests, or heterotopia, are aggregates of ectopic cortical adrenal tissue that may be present anywhere along the genitourinary tract. Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Testiculosplenic fusion

Definition A benign congenital condition that is a form of splenogonadal fusion involving the spleen and testis Clinical features Epidemiology Rare developmental condition You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…

Cryptorchidism

Definition Failure of the testis to descend from an abdominal position through the inguinal canal into the scrotum during fetal development Clinical features You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…