The shortage of cadaveric liver grafts has stimulated the development of innovative surgical procedures with various forms of living donor liver transplantation (LDLT), especially in adult patients, which produce satisfactory results comparable to whole-liver deceased donor liver transplantation (DDLT). For…
Although over 6000 people receive a liver transplant in the United States each year, more than 16,000 patients are listed. The growing gap between the demand and supply for liver grafts is one of the biggest challenges in liver transplantation.…
Split-liver transplantation and living donor liver transplantation (LDLT) in adult patients are now recognized as established treatments for end-stage liver disease. During the early days of adult LDLT, left lobe (LL) LDLT was the only option, although LL grafts constitute…
The bile ducts and vascular conduits of the harvested grafts from living donors are incomplete, thin, and short. The biliary and vascular reconstruction of living donor transplantation is therefore too technically demanding to perform by simple extrapolation of the techniques…
Orthotopic liver transplantation has now become the gold standard treatment for end-stage liver disease. However, the ongoing shortage of suitable livers, together with progressively longer waiting lists, prevents many patients from being transplanted; this has led to a significant waiting…
Pediatric liver transplantation has driven technical innovations in surgery over the past 25 years. Early successful liver transplantation relied on the use of size-matched whole-liver grafts. This requirement tended to exclude small children of less than 10 kg from liver…
In 1993 the first successful adult-to-adult living donor liver transplantation was performed using a left liver graft. Until then, liver transplantations from living donors had been performed only for pediatric recipients. Because of the overwhelming shortage of liver grafts from…
Living donor liver transplantation (LDLT) has emerged to relieve the global shortage of deceased donor liver grafts. After the first success in a child was reported by Strong et al of Brisbane in 1990, significant advancements in various fields have been…
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History and Significance of Pediatric Living Donor Liver Transplantation The first living donor liver transplantation (LDLT) in the world was performed in Brazil by Raia in December 1988, but the recipient did not survive long. The first successful LDLT was…