Transplantation of the Liver

Organ Allocation: The European Models

Liver Transplantation in Europe The number of liver transplants performed in Europe has increased, reaching a plateau of close to 6000 liver transplants performed annually ( Fig. 6-1 ). The number of listed patients waiting for a liver transplant continues…

Organ Allocation: The U.S. Model

Historical Perspective and Legislation The process of liver allocation in the United States has evolved significantly over the past 4 decades. At the time of the first transplants there was no formal allocation system. There were no established criteria defining…

Influence of Transplantation on Liver Surgery

Liver transplantation is the gold standard treatment for patients with end-stage liver disease. The great success of liver transplantation has produced a ripple effect on many other medical and scientific disciplines and, in particular, on general and hepatobiliary surgery. The…

Molecular and Cellular Basis of Liver Failure

Liver failure is the inability of the liver to perform its normal synthetic and metabolic function as part of normal physiology and arises from the loss of functional hepatic parenchyma from either acute or chronic injury. More than 30 million…

Surgical Anatomy of the Liver

The increasing organ shortage observed since the previous edition of Transplantation of the Liver mandates expert knowledge of partial allograft transplantation by the practicing clinician. The maturation of hepatobiliary surgery has expanded the role and safety of major hepatic resection,…

The History of Liver Transplantation

The history of liver transplantation is a complicated story to tell—it is a story of great successes and tragic failures. It is a story of both individual heroics and the power of collaboration. It is a story that has many…