Video 26.1 Introduction to Chapter 26, Sporadic Medullary Thyroid Carcinoma. Introduction Medullary thyroid carcinoma (MTC) comprises 1% to 2% of all new cases of thyroid cancer in the United States, a number that is significantly smaller than historically documented, due…
Video 25.1 Introduction to Chapter 25, Hürthle Cell Tumors of the Thyroid. Introduction Hürthle cell carcinoma (HCC) of the thyroid gland is an uncommon tumor, accounting for 3% to 10% of all thyroid cancers, and therefore few institutions have significant…
Introduction A defined set of clinical factors and pathologic characteristics have been used in different staging systems (e.g., Tumor, Node, and Metastases [TNM] with American Joint Committee on Cancer [AJCC]; metastasis, age, completeness of resection, invasion, and size [MACIS]; age,…
Video 23.1 Introduction to [CR] , Noninvasive Follicular Thyroid Neoplasm with Papillary-Like Nuclear Features. Introduction Noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) is a recently defined entity that was accepted by the World Health Organization (WHO) in 2017.…
Introduction Follicular thyroid cancer (FTC) is a subset of follicular cell–derived thyroid cancer. It falls within the broad category of differentiated thyroid cancer (DTC) and is the second most common histologic subtype behind papillary thyroid cancer (PTC). Unlike PTC, the…
Video 21.1 Introduction to [CR] , Papillary Carcinoma Observation. Introduction Recognizing that the incidence of papillary microcarcinoma (PMC) detected on autopsy and clinical screening studies far exceeded the prevalence of clinically apparent thyroid cancer more than 20 years ago, Miyauchi…
Video 20.1 Introduction to [CR] , Papillary Thyroid Microcarcinoma. The World Health Organization (WHO) defines papillary thyroid cancers that are 10 mm or less in maximal diameter as papillary microcarcinomas. These are frequently incidentally discovered lesions. Previously, these lesions were…
Introduction Classic papillary thyroid cancer (PTC) tends to have an indolent clinical course with low morbidity and mortality. Nonetheless, this disease has a wide spectrum of biologic and clinical behavior that can result in tumor recurrence and death, depending on…
Introduction Over the past decade, there has been an enormous expansion of knowledge regarding the molecular pathogenesis of thyroid tumors and major advances in clinically applying this knowledge to enhance diagnostic approaches to thyroid nodules and informing clinical trials and…
Video 17.1 Introduction to [CR] , Differentiated Thyroid Cancer Incidence. Incidence of Differentiated Thyroid Cancer Introduction Differentiated thyroid carcinoma (DTC) is the umbrella term that encompasses all malignancies arising from thyroid epithelial follicular cells and is the major form of…