Pulmonary Pathology

Lung Neoplasms in Infants and Children

Introduction Primary lung neoplasms in children are rare, occurring much less frequently than congenital malformations, inflammatory masses, and metastatic tumors. In one published review of pulmonary masses at a large pediatric hospital, the ratio of primary neoplasms to metastatic lesions…

Acquired and Idiopathic Disorders in Neonates and Young Children

Introduction Disorders presenting in neonates and young children comprise a heterogeneous group of conditions that can be divided into two broad categories, entities with a known etiology and those of unknown or poorly understood etiology. The well-characterized disorders include those…

Congenital, Developmental, and Inherited Disorders

Congenital and developmental disorders of the lung manifest almost exclusively in pediatric and neonatal patients and include a wide array of disorders resulting from abnormalities of lung architecture, cellular function, and metabolism. All of these disorders are uncommon, and most…

A Pattern-Based Approach to Diagnosis

Introduction Each of us follows well-established patterns as we go about our daily lives, and in turn we interact with our world through the recognition of patterns: in the people we know, the places we live, and the structures that…

The Uses and Abuses of the Lung Biopsy

Introduction The lung biopsy is widely recognized as a valuable tool for the diagnosis and management of diverse pulmonary disorders. The various procedures currently in use, such as the open lung biopsy (OLBx), video-assisted thorascopic surgery (VATS) biopsy, and transbronchial…