Principles of Neurological Surgery

Cerebellopontine Angle Tumors

Clinical Pearls Comprehensive knowledge of the complex anatomy of the cerebellopontine (CP) angle is a prerequisite for achieving good surgical results. The crucial neurovascular structures should be identified as early as possible during surgery, which enables their preservation and guides…

Pineal Region Tumors

Clinical Pearls The pineal region is bordered posteriorly by the tentorial apex, inferiorly by the culmen of the cerebellar vermis, superiorly by the splenium of the corpus callosum, and anteriorly by the third ventricle, quadrigeminal plate, and midbrain tectum. Pineal…

Convexity and Parasagittal Versus Skull Base Meningiomas

Clinical Pearls Meningiomas are the most common primary brain tumors, and the knowledge of these tumors and their management has evolved over the years. With better and more affordable radiologic investigations and changes to the World Health Organization classification grading,…

Brain Metastasis

Clinical Pearls A metastatic brain tumor means that the patient has stage IV cancer, with median survival of less than 1 year. When a patient presents with a new brain metastasis, without a known primary site, the chance of finding…

High-Grade Gliomas

Clinical Pearls High-grade gliomas are malignant brain tumors with a median survival of 14 months with maximal therapy, and they are considered incurable. Mainstays of therapy include maximal safe surgical resection combined with adjuvant radiation and chemotherapy. Although previously controversial,…

Low-Grade Gliomas

Open full size image Overview The term low-grade glioma (LGG) is used to describe World Health Organization (WHO) grade II gliomas, including diffuse astrocytomas, oligodendrogliomas, and oligoastrocytomas. Unlike high-grade gliomas, LGGs tend to grow slowly, but persistently, at roughly 3.5 mm…

Pediatric and Adult Scoliosis

Clinical Pearls The clinician must be alert for any evidence of underlying neurologic disease, including asymmetrical abdominal reflexes, abnormalities on neurologic examination, or a cavovarus foot deformity. On radiographs, hyperkyphosis over the apex of the curvature, an unusual curve pattern,…

Degenerative Spinal Disease (Lumbar)

Clinical Pearls A detailed history and neurologic exam can be used to isolate the level at which the underlying pathology originated. Understanding the presenting symptoms can help one to appreciate the significance of the extent of degeneration present and therefore…

Degenerative Spinal Disease (Cervical)

Clinical Pearls Degeneration in the spine is a naturally occurring process that can be understood through the “three-joint complex,” which is composed of the intervertebral disk and the two dorsal articulating joints. Degeneration of any one joint leads to degeneration…

Craniovertebral Junction: A Reappraisal

Clinical Pearls Atlantoaxial joint opening, manual manipulation of the facets, denuding of the articular cartilage, packing of bone graft into the joint cavity, and direct screw fixation of the facets of atlas and axis form a biomechanically strong mode of…