Definition Evidence-based medicine is the use of the highest-quality medical data currently available to assist in clinical decision making. Key Features The Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence propose the hierarchy for levels of evidence shown in…
Definition The genetic component underlying the pathogenesis of many of the heterogeneous diseases referred to as glaucoma . Key Features Congenital or juvenile onset. Common forms of glaucoma with complex inheritance. Introduction For many years a family history of glaucoma…
Definition Untoward events occurring with glaucoma surgery intraoperatively or postoperatively that can limit the success of the surgery. Key Features Can occur in the intraoperative, early postoperative, or late postoperative period. May or may not be technique dependent. May cause…
Definition Glaucoma drainage implants are surgically placed to lower intraocular pressure. They may be used at any stage in the treatment of glaucoma. Key Feature Glaucoma drainage implants bypass the natural aqueous outflow systems and typically shunt aqueous humor via…
Definition Medical and other adjunctive agents and associated surgical techniques used intraoperatively and/or preoperatively and postoperatively to modulate the wound healing associated with glaucoma surgery in an effort to increase its success. Key Features Mitomycin C. 5-Fluorouracil. Topical intraoperative use.…
Definition A surgical procedure featuring a partial-thickness scleral flap that creates a fistula between the anterior chamber and the subconjunctival space for filtration of aqueous fluid and the creation of a conjunctival bleb in an effort to lower intraocular pressure.…
Definition Minimally invasive glaucoma surgery and microincisional glaucoma surgery offer the theoretical advantages of lowering intraocular pressure with incisional surgery with fewer risks compared with conventional operations. Approaches include the use of microdevices for removal or bypass of abnormally high-resistance…
Definition Anterior segment surgical techniques for the treatment of childhood glaucoma. Key Features Angle surgery uses an ab interno or ab externo surgical approach to create a direct communication between the anterior chamber and Schlemm’s canal by incising the trabecular…
Definition Surgical and laser procedures that ablate the ciliary body to lower intraocular pressure for treatment of glaucoma. Key Features Transscleral cyclophotocoagulation. Transscleral micropulse diode laser. Endoscopic cyclophotocoagulation. Associated Features Neovascular glaucoma. End-stage glaucoma. Combined cataract surgery and endoscopic cyclophotocoagulation.…
Definition and Key Features Laser trabeculoplasty: laser treatment to the trabecular meshwork to enhance outflow of aqueous humor from the eye. Laser peripheral iridectomy: laser treatment to create a full-thickness hole within the peripheral iris to alleviate pupillary block. Associated…