Bamlanivimab With Etesevimab and Casirivimab With Imdevimab Monoclonal antibodies were first conceived as a target for disease-causing pathogens in the early 1900s by Elie Metchnikoff. This idea led to the developmental theory of immunology, in which Metchnikoff was awarded the…
This chapter focuses on the changes made at Henry Ford Health System (HFHS) in response to the coronavirus disease 19 (COVID-19) pandemic. This has been described as a “low-chance, high-impact” event that has stressed health-care systems worldwide and has required…
Acknowledgment We acknowledge the contribution by Dr. Mayur Ramesh of the Infection Diseases Service at Henry Ford Hospital, Detroit, Michigan, USA. Treatment Approach for the Hospitalized Patient With COVID-19 Introduction The goal of this chapter is to inform the neurologist…
Headache is the most common neurological symptom presenting in patients infected with COVID-19. In large retrospective studies of international populations, the incidence of headache is greater than 70%. Understanding, diagnosing, and treating these patients remain a challenge. Epidemiology Headache is…
Introduction Beyond the possibility of life-threatening consequences of pulmonary invasion and respiratory failure, COVID-19 infection imparts a wide range of neurological and neuropsychiatric consequences for many infected persons. This chapter reviews several of the problems that arise from central nervous…
Introduction Neuro-oncology is a multidisciplinary specialty dedicated to caring for those faced with neoplasms in the nervous system. Neuro-oncologists are often fellowship-trained neurologists or medical oncologists. The bulk of care is directed at primary brain tumors of which the majority…
Introduction: The Reduced Burden of COVID-19 on Childhood Because children with COVID-19 are often asymptomatic or exhibit respiratory illness of only mild-to-moderate degree, the extent of disease in childhood is difficult to define with accuracy. In reports skewed toward hospitalized…
SARS-CoV-1 caused severe acute respiratory syndrome in 2002–03 and this epidemic affected close to 8000 patients worldwide. Aggressive public health efforts to contain the virus along with relative lack of easy transmissibility limited the original outbreak. Very few neurologic complications…
Abbreviations AQP4 aquaporin 4 CNS central nervous system CSF cerebrospinal fluid FDA US food and drug administration IgG immunoglobulin G IVIG human immunoglobulin IVMP intravenous methylprednisolone MOG myelin oligodendrocyte glycoprotein MS multiple sclerosis NMO neuromyelitis optica NMOSD neuromyelitis optica spectrum…
Introduction Over time as human civilization has grown, it has faced several pandemics over thousands of years. To name a few, lately, since the beginning of the 21st century, pandemics have included swine flu (H1N1) in 2009 and two novel…