Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases

Streptococcus pneumoniae

Revised July 1, 2020 Long recognized for causing asymptomatic colonization and as a prominent cause of pneumonia, bacteremia, meningitis, sinusitis, and otitis media, Streptococcus pneumoniae is likely the most common cause of serious bacterial respiratory infection in both children and…

Streptococcus pyogenes

Revised December, 2019 Streptococcus pyogenes (group A Streptococcus; [GAS]) is one of the most important bacterial pathogens of humans. This ubiquitous organism is the most frequent bacterial cause of acute pharyngitis, and it also gives rise to a variety of…

Orientia tsutsugamushi (Scrub Typhus)

History The earliest clinical reports of possible scrub typhus date back to the Chinese manual Zhouhofang in 313 bc . In 1810 the association of a febrile illness with mite transmission was made in the Niigata Prefecture in Japan, which…