Gynecologic and Obstetric Pathology

Hidradenitis Suppurativa

D efinition —A suppurative inflammatory process that can be associated with fistula tract or abscess formation. Clinical Features Epidemiology Most commonly seen in young women. The most common sites of involvement are the axilla and groin. You’re Reading a Preview…

Epidermolytic Hyperkeratosis

D efinition —Hyperkeratosis marked by discrete, flesh- to white-colored papules to plaques. This entity overlaps with what is called acantholytic dyskeratosis (a term under which other dyskeratoses might fall). In this section we discuss a process that is encountered sporadically.…

Darier’s Disease

D efinition —Autosomal dominant genodermatosis marked by numerous hyperkeratotic papules that usually involve the trunk. Clinical Features Epidemiology Patients present around puberty; however, they can present later in life. Men are more severely affected; however, the incidence is equal in…

Hailey-Hailey Disease

D efinition —An autosomal dominant, acantholytic dermatosis with a predilection for moist body creases. Clinical Features Epidemiology It is a rare autosomal dominant disease. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…

Pemphigus Vulgaris

D efinition —An acquired autoimmune (anti–desmoglein 3 antibodies) blistering disorder that is marked by flaccid bullae and mucosal erosions. Clinical Features Epidemiology Incidence is rare and the disease may affect all age groups. You’re Reading a Preview Become a Clinical…

Bullous Pemphigoid

D efinition —An autoimmune blistering disorder that is the most common cause of subepidermal blisters. Caused by antibodies to a 230 kD plakin (BPAg1) and a 180 kD glycoprotein (BPAg2). Clinical Features Epidemiology Primarily seen in older patients and is commonly associated…

Zoon’s Vulvitis

D efinition —Plasma cell–mediated vulvitis of unknown etiology. Clinical Features Epidemiology A rare condition. Has also been reported in men, as balanitis chronica circumscripta plasmacellularis. Age range is from 25 to 70 years, with middle-aged women most commonly being affected.…

Lichen Planus

D efinition —An uncommon idiopathic mucocutaneous inflammatory dermatosis with a prototypical lichenoid tissue reaction pattern, and a wide range of clinical presentations. Clinical Features Epidemiology Women at ages of 30 to 60 years. You’re Reading a Preview Become a Clinical…

Lichen Sclerosus Including Early Lichen Sclerosus

D efinition —A chronic inflammatory dermatosis of unknown etiology that commonly affects the vulva. Clinical Features Epidemiology More commonly seen in perimenopausal and postmenopausal patients; however, can be seen at any age. Associations have been made with vulvar intraepithelial neoplasia…

Seborrheic Dermatitis

D efinition —A chronic, recurrent dermatitis occurring in areas where sebum is produced marked by red plaques with a yellow scale. Clinical Features Epidemiology Common. Affects all demographic groups. Immunosuppressed patients and patients with some chronic conditions (including congestive heart…