Gynecologic and Obstetric Pathology

Rhabdomyoma

D efinition —A solitary, benign, polypoid lesion of the vagina composed of bland rhabdomyoblasts. Clinical Features Epidemiology Middle-aged women. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

Synovial Sarcoma of the Vulva

PITFALL D efinition —A malignant frequently biphasic tumor of soft tissue. Clinical Features Epidemiology Rare. Encountered in all age groups, mostly in the second and third decades. t(X:18) translocation (representing a fusion of SYT [at 18q11] with either SSX1 or…

Liposarcoma

D efinition —A malignant neoplasm of adipocytes. Clinical Features Epidemiology Rare. Most commonly encountered in middle-aged women. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member.…

Lipoma

D efinition —A benign adipocytic neoplasm. Clinical Features Epidemiology Rarely encountered in the vulva. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Low-Grade Fibromyxoid Sarcoma

D efinition —A painless, deep-seated, and slow-growing tumor with a deceptively bland histologic appearance and a propensity for local recurrence. Clinical Features Epidemiology Low-grade fibromyxoid sarcoma (LGFMS) is uncommon. Most often identified in children and young to middle-aged adults. The…

Dermatofibrosarcoma Protuberans

D efinition —A subcutaneous, locally aggressive spindle cell neoplasm with a storiform growth pattern and honeycomb-like infiltration into adipose tissue. Clinical Features Epidemiology Dermatofibrosarcoma protuberans involving the vulva is rare; however, cases have been reported. You’re Reading a Preview Become…

Dermatofibroma (Fibrous Histiocytoma)

D efinition —A benign fibrohistiocytic tumor of dermal stroma, composed of spindle cells with a storiform (pinwheel) growth pattern. Clinical Features Epidemiology Occurs in adults. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Cellular Angiofibroma

D efinition —A benign subcutaneous neoplasm composed of short fascicles of spindle cells with prominent small, thick-walled, blood vessels. Clinical Features Epidemiology Uncommon. Typically seen in middle-aged women (mean age ~55 years). You’re Reading a Preview Become a Clinical Tree…

Superficial Angiomyxoma

D efinition —A benign pedunculated myxoid soft tissue neoplasm with a tendency toward local recurrence. Clinical Features Epidemiology Rare. Occasionally occurs in the vulva. Most frequently seen in reproductive-age women in their 30s. You’re Reading a Preview Become a Clinical…

Aggressive Angiomyxoma

PITFALL D efinition —A bland, hypocellular, spindle cell lesion of the vulvar/perineal region with a tendency for local infiltration and recurrence. Clinical Features Epidemiology Reproductive-age women in their 30s. Uncommon. You’re Reading a Preview Become a Clinical Tree membership for…