Gynecologic and Obstetric Pathology

Adenomyoma of the Cervix

D efinition — A benign, discrete proliferation of smooth muscle stroma and endocervical glands. Clinical Features Epidemiology Adenomyomas and polypoid adenomyomas of the cervix are rare. The majority of these lesions occur within the uterine cavity, not at the cervix.…

Atypical Endocervical Polyp

D efinition — An endocervical polyp with an atypical epithelial-stromal proliferation that resembles adenosarcoma but is not diagnostic. Clinical Features Epidemiology Uncommon but will be encountered. No predisposing factors have been identified. You’re Reading a Preview Become a Clinical Tree…

Metastatic Endometrioid Carcinoma to the Cervix

D efinition — Endometrial adenocarcinoma which has spread caudally to involve the cervix. Clinical Features Epidemiology Varies with the subtype of endometrial adenocarcinoma. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become…

Metastatic Serous Carcinoma to the Cervix

D efinition — Serous carcinoma originating from the upper genital tract involving the cervix (drop metastasis). Clinical Features Epidemiology Uncommon. Women in their 60s to 70s. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy…

Endocervical Glandular Hyperplasia

D efinition — An increase in the number of endocervical glands. May be idiopathic or secondary to increased hormonal stimulation. Some atypical hyperplasias may be associated with minimal deviation adenocarcinomas and Peutz-Jeghers syndrome (see page 300 ). Clinical Features Epidemiology…

Prostatic Metaplasia of the Cervix

D efinition — The histologic appearance of large prostatic duct–like tissue within the cervical stroma. Clinical Features Epidemiology Prostatic metaplasia is a rare (or possibly under-reported) process. There is no age predilection. You’re Reading a Preview Become a Clinical Tree…

Mesonephric Carcinoma

D efinition — A carcinoma derived from mesonephric remnants located in the lateral walls of the uterine cervix. Clinical Features Epidemiology Very rare. The mean age at presentation is early 50s. You’re Reading a Preview Become a Clinical Tree membership…

Mesonephric Remnants

D efinition — Embryologic remnants of mesonephric differentiation found in the gynecologic tract. Clinical Features Epidemiology Mesonephric remnants may be identified in up to one fifth of well-sampled cervices. No age or demographic predilection has been identified. You’re Reading a…

Adenoid Basal Carcinoma

D efinition — Adenocarcinoma composed of basaloid cells with areas of columnar cell differentiation. Clinical Features Epidemiology Rare; accounts for less than 5% of cervical carcinomas. Usually seen in postmenopausal women. Human papillomavirus (HPV) associated. African-American women are affected more…

Signet-Ring Cell Carcinoma of the Cervix

D efinition — A rare variant of invasive adenocarcinoma originating in the endocervix. Clinical Features Epidemiology Limited to case reports. Wide age range, but most present in the fourth or fifth decade. Human papillomavirus (HPV) associated. May be found with…