Gynecologic and Obstetric Pathology

Disseminated Peritoneal Leiomyomatosis

D efinition — An uncommon disorder marked by the presence of multiple smooth muscle tumors that are scattered throughout the peritoneum and omentum. Clinical Features Epidemiology Disseminated peritoneal leiomyomatosis (DPL) is a rare disorder. It is most commonly seen in…

Morcellation-Related Dissemination of Smooth Muscle Neoplasia

D efinition — A specific syndrome caused by the iatrogenic dissemination of a morcellated smooth muscle tumor, which is distinct from spontaneous disseminated peritoneal leiomyomatosis. Clinical Features Epidemiology Power morcellation has been a commonly used technique for removing intraabdominal smooth…

Intravenous Leiomyomatosis

D efinition — A variant of leiomyoma in which the tumor is located entirely within vein(s) of the uterus, pelvis, or even the vena cava. Clinical Features Epidemiology Rare. Same patient population as typical uterine leiomyoma. You’re Reading a Preview…

Intravenous Leiomyoma

D efinition — An unusual smooth muscle tumor of the uterus with a predilection for vascular involvement. Clinical Features Epidemiology Rare. Same patient population as for usual leiomyoma. You’re Reading a Preview Become a Clinical Tree membership for Full access…

Leiomyomatosis

D efinition — Uterine smooth muscle tumor composed of multiple repetitive fascicles of smooth muscle diffusely involving the myometrium without a definable border. Clinical Features Epidemiology Same as for leiomyoma, but extremely rare. You’re Reading a Preview Become a Clinical…

Atypical Leiomyoma (Leiomyoma with Bizarre Nuclei)

D efinition — A benign smooth muscle tumor with prominent nuclear atypia. Clinical Features Epidemiology Uncommon. Identified in the same patient population as typical leiomyomata. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Mitotically Active Leiomyoma

D efinition — A morphologic variant of uterine leiomyoma. Clinical Features Epidemiology Mitotic activity within normal and leiomyomatous smooth muscle cells is a well-established phenomenon. Exogenous progesterones increase the observed mitotic rate in leiomyomata. You’re Reading a Preview Become a…

Hydropic Leiomyoma

D efinition — Uterine smooth muscle tumor with prominent degenerative changes. Clinical Features Epidemiology Same as for leiomyoma. Degenerative change within leiomyomata is extremely common. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited…

Cellular Leiomyoma

D efinition A smooth muscle tumor with conspicuous increased cellularity. Clinical Features Epidemiology The same as for usual leiomyoma. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

Lipoleiomyoma

D efinition — A benign tumor of the uterus composed of both smooth muscle and adipose cells. Clinical Features Epidemiology Rare. Postmenopausal women. t(12;14) a common chromosomal rearrangement similar to other leiomyomas. You’re Reading a Preview Become a Clinical Tree…