Gynecologic and Obstetric Pathology

Xanthogranulomatous Salpingitis

D efinition — An admixture of inflammatory cells and histiocytes within the fallopian tube. Clinical Features Epidemiology Xanthogranulomatous salpingitis is an uncommon entity. It is most commonly seen in association with pelvic inflammatory disease, extensive endometriosis, and intrauterine contraceptive devices.…

Pseudoxanthomatous Salpingiosis

D efinition — Accumulation of histiocytic cells within the fallopian tube in association with pelvic endometriosis. Clinical Features Epidemiology Pseudoxanthomatous salpingiosis is an uncommon entity that may be found in association with endometriosis. You’re Reading a Preview Become a Clinical…

Adrenal Rest

D efinition — A developmental rest of adrenal tissue in the adnexal soft tissue. Clinical FeatureS Epidemiology Can be seen at all ages and in up to one fourth of fallopian tubes examined. Presumably adrenal rests are misplaced deposits of…

Reproductive Tract Lymphoma

D efinition — A malignant lymphoid process involving the reproductive tract. Clinical Features Epidemiology Reproductive tract lymphoma is exceedingly rare but about two thirds will be primary tumors. In about one third of cases the tumor will be a manifestation…

PEComa

D efinition — A tumor composed of a morphologically and immunohistochemically distinct cell type with features of smooth muscle and melanocytic differentiation. Clinical Features Epidemiology Very rare; a somewhat controversial diagnosis at this site (uterus). Cases have been reported in…

Epithelioid Leiomyosarcoma

D efinition — A distinctive histopathologic variant of uterine leiomyosarcoma. Clinical Features Epidemiology Rare. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here

Myxoid Leiomyosarcoma

D efinition — An aggressive histologic variant of uterine leiomyosarcoma. Clinical Features Epidemiology Rare, even among uterine leiomyosarcomas. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a…

Leiomyosarcoma

D efinition — A malignant tumor of smooth muscle originating in the myometrium. Clinical Features Epidemiology Rare (estimated incidence of 0.64 per 100,000 women). Account for 1% of all uterine malignancies and more than 25% of uterine mesenchymal malignancies. Mostly…

Hereditary Leiomyomatosis and Renal Cell Carcinoma Syndrome

PITFALL D efinition — A unique variant of uterine smooth muscle tumor associated with a genetically transmitted increased risk of renal cell carcinoma (RCC) (loss of heterozygosity [LOH] at 1q43). Clinical Features Epidemiology The underlying defect is a germ-line heterozygous…

Pathology Following Uterine Artery Embolization

D efinition — Changes in the myometrium following an embolization procedure for a presumed leiomyoma using synthetic material. Clinical Features Epidemiology Uterine embolization procedures are performed about 25,000 times per year in the United States. You’re Reading a Preview Become…