Gynecologic and Obstetric Pathology

Polycystic Ovarian Syndrome

D efinition — An apparent congenital disorder characterized by ovulatory dysfunction and biochemical evidence of androgen excess, often with polycystic ovaries detected by ultrasound. Clinical Features Epidemiology First described by Stein and Leventhal. Can be seen in generations of families,…

Solitary Luteinized Follicle Cyst

D efinition — Benign incidental ovarian cyst most often noted in pregnant women. Clinical Features Epidemiology Uncommon to rare. Most often noted in pregnant or recently postpartum women. Can also be seen in nonpregnant, usually reproductive-age, women. You’re Reading a…

The Ovary in Pregnancy

D efinition — A constellation of findings in the ovary during gestation. Clinical Features Epidemiology Related to the pregnancy state. Linked to the effects of gonadotropins on the ovarian cortex. Can be particularly pronounced during multiple-gestation pregnancies and hydatidiform moles.…

Tangentially Sectioned Ovarian Follicle

PITFALL D efinition — A benign sectioning artifact that can be mistaken for neoplasia. Clinical Features Epidemiology Reproductive-age women. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are…

Female Adnexal Tumor of Wolffian Origin

D efinition — A low-grade neoplasm that is thought to arise in the mesonephric remnants of the broad ligament. Clinical Features Epidemiology Female adnexal tumors of (probable) wolffian origin (FATWOs) are rare neoplasms, and no clinical or demographic associations have…

Endosalpingeal Implants from Remote Tumors

D efinition — Intraepithelial neoplasms of presumed nontubal origin. Clinical Features Epidemiology Uncommon but a function of the thoroughness to which the tube is examined. Can be seen with both gynecologic and nongynecologic tumors. Mucosal involvement will be seen in…

Adenocarcinoma of the Fallopian Tube

D efinition — Adenocarcinoma arising in the tubal mucosa. Clinical Features Epidemiology Historically a small fraction (5% or less) of pelvic serous carcinomas relative to the ovary; however, with the attention being paid to the distal tube (using the section…

Salpingoliths

D efinition — Psammous calcifications in the lumen and plica of the fallopian tube. Clinical Features Epidemiology Uncommon. Approximately one half are associated with low-grade serous tumors of the ovary (borderline or low-grade malignancies). You’re Reading a Preview Become a…

The Risk Reducing Salpingo-Oophorectomy

D efinition — A procedure designed to remove the tubes and ovaries prior to the development of malignancy in women at high risk for ovarian cancer (BRCA1/2 germ-line mutations). Clinical Features Epidemiology Heterozygous germ-line mutations in BRCA1 or BRCA2 occur…