D efinition — A distinctive constellation of patterns (solid, endometrioid-like, and transitional [SET]). Defined (arbitrarily) as greater than 50% of the tumor. Clinical Features Epidemiology Frequently associated with BRCA1 or BRCA2 germline mutation (approximately 50%). This pattern is seen less…
D efinition — A pelvic serous carcinoma with papillary architecture and high nuclear grade. Clinical Features Epidemiology Approximately 15% associated with BRCA1 or BRCA2 germline mutation. Predominant in the sixth and seventh decades of life. Approximately 1% of women will…
D efinition — A granulomatous disease of uncertain etiology characterized by histiocytic infiltrates (von Hansemann cells) with calcified inclusions (Michaelis-Gutmann bodies). Clinical Features Epidemiology Most often associated with the urinary tract with a female preponderance (4 : 1). There is no relationship…
D efinition — The presence of epithelium resembling fallopian tube epithelium outside the fallopian tube. Clinical Features Epidemiology Endosalpingiosis has been noted in up to 7% of reproductive-age women. It can be found in association with other pelvic pathologic processes…
D efinition — Ovarian cortical inclusion cysts (CICs) lined by either mesothelium (ovarian surface epithelium [OSE]) or müllerian epithelium. Clinical Features Epidemiology Very common. Found in the majority of ovaries in postmenopausal women. Associated with increasing age. Most plausible origin…
D efinition — A benign epithelial or epithelial stromal tumor with a serous (ciliated) epithelial component. Clinical Features Epidemiology Common; among the most frequently encountered of the benign epithelial tumors. Can be seen at any age, most commonly in postmenopausal…
PITFALL D efinition — A variant of endometrioma that may be confused with malignancy on ultrasound. Clinical Features Epidemiology Relatively common. Seen during pregnancy. You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles…
D efinition — Endometriotic epithelium with noncomplex architecture and nuclear atypia. Clinical Features Pathogenesis Occurs in endometriotic cysts. Possibly a very early neoplastic change akin to other lesions associated with endometriomas, such as müllerian mucinous cystadenomas, adenofibromas, and well-differentiated endometrioid…
D efinition — Endometriotic epithelium with focal noncomplex mucinous differentiation. Clinical Features Pathogenesis Occurs in endometriotic cysts. Probably a very early neoplastic change akin to other lesions associated with endometriomas, such as müllerian mucinous cystadenomas, adenofibromas, and well-differentiated endometrioid adenocarcinomas.…
D efinition — An expansion of the ovarian cortex and medulla by a benign proliferation of ovarian cortical stromal cells and associated luteinized cells. Cortical stromal hyperplasia (CSH) is a mild form seen at menopause; stromal hyperthecosis is a more…