Gray's Anatomy

Cell populations at gastrulation

Conceptus with a Bilaminar Embryonic Disc At stage 6 the conceptus is composed of the walls of three cavities. The large chorionic cavity is surrounded by a meshwork of trophoblast and developing villi, and lined with extraembryonic mesoblast. The chorion,…

Implantation and placentation

Implantation Implantation involves the initial attachment of the trophoblastic wall of the blastocyst to the endometrial luminal epithelium, stimulating the decidual response. The blastocyst is present within the uterine cavity for some 72 hours prior to implantation, and during this…

Preimplantation development

Understanding the spatial and temporal developmental processes that take place within an embryo as it develops from a single cell into a recognizable human is the challenge of embryology. The control of these processes resides within the genome; fundamental questions…

A critical evaluation of the current status of myofascial chains

Introduction From a morphological point of view, most anatomy textbooks have described the skeletal muscles of the human body as being discrete actuators with clear origins and insertions ( ). Recent analyses of published anatomical cadaveric studies have challenged this…

The reaction of peripheral nerves to injury

Main nerve trunks contain many thousands of axons. When a trunk is stretched, but not ruptured, by dislocation of, say, the femoral or humeral heads, or by the nearby passage of a bullet, the axons within that nerve may respond…

Merkel cells

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Metaplasia

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Electron microscopy in the twenty-first century

Introduction Biological electron microscopy (EM) is pivotal in life science research. A measure of its ubiquity is the diversity of its capacity, e.g. three-dimensional structural information about proteins and viruses at Å resolution; three-dimensional reconstructions of cellular organelles and tissues…

Skin and its appendages

In this chapter, the types and functions of skin in different parts of the body are described first, followed by the microstructure of the epidermis and dermis, and the appendages of skin, including the pilosebaceous units, sweat glands and nails.…