Introduction Embryogenesis results from the divergent proliferation, migration, survival, and differentiation of cells derived from a single cell, the fertilized egg. Regulatory signals, applied to successive generations of cells, establish the architecture of the early embryo. The same processes are…
Acknowledgments We thank Dr. Stanley Kaplan for his valuable contributions to the previous edition of this chapter. Introduction The human embryo begins as a single large cell, approximately 0.1 mm in diameter, just visible to the unaided eye. During the…
Principles of Epigenetics Introduction to Epigenetics The publication of the majority of the human genome sequence in 2001 , was the precursor to many important discoveries. However, the human genome sequence has not provided researchers with the codex to fully…
Introduction The human genome refers to the complete set of human DNA (with the suffix -ome arising from the Greek for “all” or “complete”). A copy of our genome comprises approximately 3 billion base pairs (bp) and about 20,000 protein-coding…