Physical Address
304 North Cardinal St.
Dorchester Center, MA 02124
Post-Term Pregnancy
You’re Reading a Preview Become a Clinical Tree membership for Full access and enjoy Unlimited articles Become membership If you are a member. Log in here
Obstetric Management of Multiple Gestation and Birth
The human female is programmed by nature to mono-ovulate, to nurture one fetus, and to take care of one neonate at a time. This natural pattern results in the relatively rare birth of twins (about 1 per 80 to 100…
Fetal Effects of Autoimmune Disease
Placental Transfer: General Remarks The maternal-fetal interface is quite efficient in its selective exclusion of substances during the transport process from the maternal to the fetal circulation. At the same time, the placenta selectively transfers other substances, a process that…
Obstetric Management of Prematurity
Preterm birth is defined as a delivery that occurs at 20 weeks’ gestation or later but prior to 37 weeks’ gestation (from the first day of the last menstrual period). Although advancements in neonatology and obstetrical interventions have dramatically improved…
Pregnancy Complicated by Diabetes Mellitus
In the United States, depending on the applied diagnostic criteria, 135,000-200,000 women develop gestational diabetes mellitus (GDM) annually, adding to the number of pregnant women diagnosed with either type 1 or type 2 diabetes. Of greater concern may be the…
Hypertensive Disorders of Pregnancy
Hypertensive disorders of pregnancy consist of a broad spectrum of medical complications, including gestational hypertension, preeclampsia, eclampsia, and pregestational hypertension. The incidence is estimated to be between 3% and 10% of all pregnancies. Worldwide, preeclampsia and related conditions are among…
Developmental Origins of Adult Health and Disease
Fetal Origins of Adult Disease Concept The concept of fetal origins of adult disease popularized by Barker arose from a robust association between small size at birth and the risk of chronic adult diseases, such as coronary artery disease, hypertension,…
Intrauterine Growth Restriction
Summary Intrauterine growth restriction (IUGR) broadly encompasses pregnancies complicated by poor fetal growth, where the fetus's growth is less than its genetic potential. IUGR is an important condition to recognize, as it is a common complication of pregnancy that has…
Adverse Exposures to the Fetus and Neonate
Exposure to environmental toxicants during pregnancy may have a significant impact on the developing fetus. Fetal adverse exposures are growing in importance as our population expands and the number of women participating in the workforce continues to rise. In 2015,…
Surgical Treatment of the Fetus
Summary Over the past half-century, implementation of high-resolution screening prenatal imaging, coupled with increasingly nuanced understanding of embryology and human fetal development, have created a new surgical patient: the fetus. Through decades of rigorous scientific investigation and technical innovation, congenital…