Risk Cancer is the second most common cause of death in USA. In 2016, about 1,685,210 pts will be diagnosed with cancer and 595,690 will die of it. More than two-thirds of all cancers are diagnosed in people 50 y…
Uses Synthesized in 1953, introduced for trigeminal pain in 1962 and for epilepsy in 1965; approved by the USA FDA since 1976 for the following: Epilepsy: Generalized tonic-clonic seizures, partial seizures with complex pathology (psychomotor, temporal), partial seizures with or…
Uses Topical analgesic treatment for diabetic polyneuropathy, postherpetic neuralgia, and other peripheral neuropathic pain; also for osteoarthritis, rheumatoid arthritis, and other painful disorders Spray used as nonlethal force by law enforcement Perioperative Risks None reported. After exposure to aerosolized capsaicin…
Uses Prescribed to treat Htn, angina, supraventricular arrhythmias, cerebral vasospasm, and HCM. Perioperative Risks CCBs are used chronically in a significant proportion of the surgical population. CCBs are utilized in the treatment of Htn, CAD, or supraventricular arrhythmias and syndromes…
Uses Management of opioid addiction Management of chronic pain (“off-label” use for SL buprenorphine and buprenorphine TD patch) Perioperative Risks Challenges in pain management throughout periop period Respiratory depression Can cause neonatal abstinence syndrome You’re Reading a Preview Become a…
Uses Treatment of squamous cell carcinoma Treatment of melanomas and sarcomas Treatment of testicular carcinoma Treatment of Hodgkin and non-Hodgkin lymphoma Sclerosing agent for malignant pleural effusion Perioperative Risks Adverse effects >10%. Acute febrile reactions (25 -50%). Dermatologic: Skin thickening,…
Uses Oral bisphosphonates: Alendronate (Fosamax), risedronate (Actonel): Prevention and treatment of postmenopausal osteoporosis, prevention and treatment of glucocorticoid-induced osteoporosis, treatment of osteoporosis in men, and Paget disease of bone Etidronate (Didronel): Prevention and treatment of postmenopausal osteoporosis and Paget disease…
Uses Available PO and IV. Prescribed long term for stable angina, systolic CHF, MI (secondary prevention), Htn, and AFIB (for control of heart rate). No longer considered first-line Rx for essential Htn, especially in elderly pts. Long-term Rx must be…
Uses Prescribed for the treatment of anxiety Used for premedication and procedural (moderate and deep) sedation Perioperative Risks High levels associated with hypnosis, unconsciousness, apnea/respiratory depression Worry About Combination (synergy) with opioids and other CNS depressants may result in severe…
Uses People in USA consume 10,000–20,000 tons annually. Rx for mild and/or moderate pain, fever, arthritis, and prevention of MI. Perioperative Risks Peptic ulcer disease Plt dysfunction Increased bleeding risk Stroke Interstitial nephritis Reye syndrome Worry About Displacement of protein-bound…