Drugs During Pregnancy and Lactation

Industrial chemicals and environmental contaminants

4.18.1 Persistent organochlorine compounds (pesticides, polychlorinated biphenyls and dioxins) Experience Within this group are the classic pesticides dichlordiphenyltrichlorethan (DDT), hexachlorbenzene (HCB), dieldrin , hexachlorcyclohexan (HCH), and “synthetic oils” made from polychlorinated biphenyls (PCBs) as well as the polychlorinated dioxins and…

Plant toxins

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Recreational drugs

Breastfeeding mothers should avoid recreational drug use wherever possible. However, the value of breastfeeding to both mother and infant is such that it likely outweighs the risks associated with most maternal recreational drug use. The risks should be discussed on…

Infections during breastfeeding

Even when the general condition of the mother with an infection would permit breastfeeding, various aspects must be considered, i.e. whether symptoms in the infant would be expected from the medication prescribed and whether transmission of the illness through the…

Contrast media, radionuclides and diagnostics

X-ray studies, ultrasound and magnetic resonance imaging (MRI) do not require an interruption of breastfeeding. This also applies to mammography and computer tomography without contrast media. Limitations apply for iodine- and gadolinium-containing contrast media and radioisotopes. Before applying contrast media…

Alternative remedies, vitamins, and minerals

4.13.1 Alternative remedies and phytotherapeutics Experience Numerous surveys in the literature report widespread use of alternative remedies with no knowledge of the risks. The interest in, and experimentation with, alternative remedies has increased in the last decades. Just as in…

Hormones and hormone antagonists

The hormone and hormone antagonists prescribed during lactation have such a wide variety of substances that a summary would do no justification to the different issues dealt with here. 4.11.1 Pituitary and hypothalamic hormones Experience There are only a few…

Immunomodulating and antineoplastic agents

Systemic auto-immune diseases commonly affect women during childbearing years. The control of maternal disease activity during pregnancy and lactation is imperative. With azathioprine, selective immune suppressants, some monoclonal antibodies or interferons, many breastfeeding mothers have sustained periods of disease quiescence…

Psychotropic drugs

4.9.1 Introduction Psychiatric diseases frequently affect women of reproductive age and particularly during postpartum period. In the case of monotherapy, most psychopharmaceuticals are acceptable during lactation period. However, some drugs have more reassuring data than others. Therefore, careful selection should…