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Benign Lymphocytic Infiltrates Lymphocytic Infiltrate of Jessner A benign skin-limited disorder that overlaps with other entities, including dermal lupus erythematosus, cutaneous lymphoid hyperplasia, and polymorphic light eruption (PMLE). Males = females; onset typically during middle age; very rare in children.…
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Spectrum of disorders caused by proliferation and accumulation of mast cells in the skin and/or other tissues ( Table 96.1 ). Table 96.1 WHO classification of mastocytosis. Cutaneous mastocytosis (CM) Maculopapular CM/“urticaria pigmentosa” Diffuse CM Mastocytoma (≤3 lesions) Systemic mastocytosis…
Neural/Neuroendocrine Neurofibroma Skin-colored to pink, soft papulonodule, often on the trunk (see Fig. 50.2 ). Compressible (the tumor often herniates inward upon palpation – this is referred to as the “button-hole” sign); it is sometimes pedunculated. Usually solitary in most…
Lesions of vascular origin are broadly, and somewhat imperfectly, classified as neoplasms (tumors), malformations, reactive proliferations, or telangiectasias. The growth of a neoplasm is largely autonomous (i.e. not reactive). Malformations, in general, are not actively proliferating (see Ch. 85 ).…
A malignant tumor of melanocytes, most commonly arising from cutaneous melanocytes; can also develop from melanocytes residing elsewhere – e.g. in the uveal tract, retinal pigment epithelium, gastrointestinal mucosa, or leptomeninges. Some cutaneous melanomas (CMs) arise de novo , whereas…
Benign Pigmented Cutaneous Lesions Other Than Melanocytic Nevi This group of lesions can further be divided into: (1) predominantly epidermal lesions ( Table 92.1 ; Figs 92.1–92.5 ); and (2) dermal melanocytoses ( Table 92.2 ; Figs 92.6 and 92.7…