Objectives This chapter will: 1. Identify the mechanisms of renal damage induced by nonsteroidal antiinflammatory drugs (NSAIDs) and coxibs. 2. Describe the incidence and epidemiology of NSAID-induced acute kidney injury. 3. Describe the risk factors for NSAID-induced acute vasomotor renal…
Objectives This chapter will: 1. Characterize major nephrotoxic chemotherapy agents and their effect on kidney function and electrolyte homeostasis. 2. Describe strategies aimed at preventing and alleviating chemotherapy-induced acute kidney injury. 3. Provide guidelines for administration of chemotherapeutic agents to…
Objectives This chapter will: 1. Describe the importance of timely acute kidney injury (AKI) diagnosis according to available guidelines. 2. Discuss the importance of early diagnosis of AKI in the emergency department (ED) and how physicians should manage the patients…
Objectives This chapter will: 1. Describe the epidemiology of diabetic kidney disease and the burden of illness in the intensive care unit (ICU) setting. 2. Illustrate the spectrum of renal disease observed in patients with diabetes in the ICU. 3.…
Objectives This chapter will: 1. Describe the pathophysiologic mechanisms underlying the development of acute-on-chronic (AoC) kidney dysfunction and its role in the progression toward end-stage kidney disease (ESKD). 2. Identify the most common clinical presentations of critical illness among chronic…
Objectives This chapter will: 1. Discuss the causes and risk factors of delayed graft function (DGF). 2. Describe the pathophysiology of ischemia/reperfusion damage. 3. Address the question of whether DGF is associated with an increased risk of acute rejection and…
Objectives This chapter will: 1. Discuss the period from renal transplantation to the first week after surgery. 2. Describe the evaluation of patients immediately before transplantation. 3. Discuss the evaluation and management of patients immediately after surgery. 4. Address techniques…
Objectives This chapter will: 1. Outline an overall approach to evaluating renal transplant recipients. 2. Identify risk factors for graft loss and death after transplantation. 3. Identify renal diseases known to recur after transplantation. 4. Identify the basic cardiac evaluation…
Objectives This chapter will: 1. Discuss the use of antibiotics in newborns admitted to intensive care units because of prematurity or severe diseases. 2. Discuss the choice of the proper antibiotic according to the clinical situation and the potential renal…
Objectives This chapter will: 1. Describe the current modalities currently available for pediatric continuous renal replacement therapy, giving context to the differences and indications for peritoneal dialysis and extracorporeal dialysis. 2. Present some general rules to follow to rationally prescribe…