Comprehensive Gynecology

Reproductive genetics

Key points Virtually all human diseases have an underlying genetic component. All health care professionals need a basic level of familiarity with genetics and genomics because it is an integral part of mainstream medicine. Genetic variation between healthy individuals exists…

Fertilization and embryogenesis

Key points Oocyte meiosis is arrested in prophase I from the fetal period until a luteinizing surge (LH) preceding ovulation. With the LH surge, the oocyte completes meiosis I associated with a decrease to 23 chromosomes with diploid (2 N…