Questions Q12.1 Concerning ivermectin therapy for scabies, (1) how does ivermectin compare with topical permethrin in success rate, and (2) is ivermectin alone effective treatment for crusted scabies? (Pgs. 126×2, 127) Q12.2 What are several mechanisms of action for ivermectin…
Questions Q11.1 What is the spectrum of dermatologic conditions that human herpes virus (HHV) infections can cause? (Pg. 115, Table 11.1 ) Q11.2 What are the two primary steps (one step with two parts) by which acyclovir reaches the form…
Questions Q10.1 What are several of the drugs currently available for systemic fungal indications or in the drug development process that have a future role in dermatologic drug therapy? (Pg. 100) Q10.2 Considering terbinafine, itraconazole, and fluconazole, (1) which drug…
Questions Q9.1 What are some dermatologic indications of antibiotic use in chronic inflammatory skin disorders, based on their anti-inflammatory properties? (Pgs. 70, 86×3) Q9.2 Which antibiotic classes have significant alterations in bioavailability because of foods and divalent cations? (Pgs. 73,…
Questions Q8.1 Concerning product labeling for a specific drug, (1) what are the four components of the ‘label,’ (2) what is the purpose of the label, and (3) what are ways that some flexibility is built into the process? (Pg.…
Questions Q7.1 How is pharmacovigilance defined? (Pg. 54) Q7.2 What are some recent examples of drugs removed from the market by the US Food and Drug Administration as a result of the pharmacovigilance process (as well as the reason for…
Questions Q6.1 In the broadest sense, what are the general areas of oversight by the US Food and Drug Administration (FDA)? (Pg. 49) Q6.2 Approximately what percentage of the FDA budget comes from user fees? (Pg. 49) Q6.3 Concerning the…
Questions Q5.1 Why is a uniform treatment approach for all patients with a given dermatosis inappropriate? ( Pg. 40 ) Q5.2 How do you communicate the uncertainty of a diagnosis or treatment plan to a patient? ( Pg. 41 )…
Questions Q4.1 What is the most basic definition of adherence in clinical practice? (Pg. 34) Q4.2 What is the estimated cost to the US healthcare system of poor adherence in terms of (1) percentage of hospital admissions, and (2) total…
Questions Q3.1 How are ‘polymorphism’ and ‘variability’ defined in the most basic sense? (Pg. 22) Q3.2 Regarding the cytochrome P-450 (CYP) isoforms discussed in this chapter, (1) which isoforms are most important to drug interactions, and (2) which of these…